Clinical management of COVID-19 (2025)

WHO develops most up-to-date technical guidance for clinical management of COVID-19 patients, including optimized supportive care interventions and therapeutics based on ongoing “living” assessment of new evidence generated by the global community. This work is supported by the Guidelines Development Group.It also:

  • Hosts the  Global COVID-19 Clinical Data Platform for clinical characterization and management of hospitalized patients with suspected or confirmed COVID-19.
  • Develops COVID-19 Clinical Management training resources for health workers based on the most up-to-date clinical guidance for online or download hosted on the WHO Academy and OpenWHO platforms.
  • Hosts the global COVID-19 Clinical Management web series for health workers, health researchers and health policy makers.
  • Convenes the Clinical Characterization and Management Research Working Group, to advance clinical research.
  • Convenes the Global Clinical Management Network, bringing together front-line clinicians from all over the world, to share expertise and experience in a peer-to-peer knowledge exchange forum.
  • Produces tools for Member States to support operational decision making, medical supply forecasting and access for essential medicines and supplies to manage COVID-19 inventory.

Health care readiness

Therapeutics and COVID-19

Oxygen Access Scale Up

Oxygen health topic

Post COVID condition

Publications

Clinical management of COVID-19 (1)

18 August 2023

Clinical management of COVID-19: Living guideline, 18 August 2023

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The WHOCOVID-19 Clinical management: living guidancecontains the most up-to-date recommendations for the clinical management of people with COVID-19. Providing guidance that is comprehensive and holistic for the optimal care of COVID-19 patients throughout their entire illness is important. Thelatest versionis available inpdfformat (via the ‘Download’ button) and via anonline platform, and is updated regularly as new evidence emerges.

Clinical Management of COVID-19 Resources for Health workers

Clinical Management of COVID-19: Acute hypoxaemic respiratory failure and COVID-19 and use of non-invasive respiratory support modules

Clinical management of COVID-19 (2)

Clinical management of COVID-19 (3)

5 August 2022

Management of critical COVID-19 Advanced non-invasive respiratory support: high-flow nasal oxygen and...

For patients on HFNO with persistent hypoxaemia or respiratory distress:• Check the equipment: inspect the exterior of the machine, the tubing (circuit),...

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Clinical management of COVID-19 (4)

5 August 2022

Management of critical COVID-19 Advanced non-invasive respiratory support: high-flow nasal oxygen and...

For patients on NIPPV or HFNO with persistent hypoxaemia or respiratory distress:• Check the equipment: inspect the exterior of the machine, the tubing...

Download

Read More

Clinical management of COVID-19 (5)

5 August 2022

Management of critical COVID-19: Acute hypoxaemic respiratory failure and COVID-19

WHO recommends prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond...

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Clinical management of COVID-19 (6)

5 August 2022

Management of critical COVID-19Advanced non-invasive respiratory support: high-flow nasal oxygen...

WHO recommends prompt recognition of progressive acute hypoxaemic respiratory failure when a patient with respiratory distress is failing to respond...

Download

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The COVID-19 CARE pathway

The COVID-19 CARE pathway reflects the current recommended clinical and therapeutic recommendations to be considered in the care plan of patients with COVID-19

Clinical management of COVID-19 (8)

6 April 2022

Clinical care of severe acute respiratory infections – Tool kit

COVID-19 adaptation, update 2022

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Clinical management of COVID-19 (9)

9 February 2022

COVID-19 home care bundle for health care workers

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COVID-19 Clinical Management Webinar Series

Clinical management of COVID-19 (10)

COVID-19 Case Management Webinar Series: Insights to therapeutic guidance development and a review of current recommendations 11 May 2021 13:30 – 15:30 CET
COVID-19 Case Management Webinar Series: Home based and Community care models for mild and moderate COVID-19 4 August 2021 13:30 – 16:00 CET
WHO COVID-19 Case Management Webinar Series: Optimising Care for Patients with Severe COVID-19 Disease 31 August 2021 13:30 – 15:30 CET
COVID-19 Case Management Webinar Series: COVID-19 and pregnancy 11 January 2022 13:30 – 15:30 CET
COVID-19 Case Management Webinar Series: COVID-19 in children and young persons 22 March 2022 13:30 – 15:30 CET
COVID-19 Case Management Webinar Series: Care of the critical patient 21 June 2022 13:30 – 15:30 CET

Clinical Management of COVID-19 learning platforms

Develops training materials for health care workers based on the most up-to-date clinical guidance, available via the WHO Academy and OpenWHO platforms:

Departmental news

3 July 2022 Departmental update WHO and ESICM release COVID-19 critical care course for nurses and doctors

Publications

Clinical management of COVID-19 (13)

18 August 2023

Clinical management of COVID-19: Living guideline, 18 August 2023

The WHOCOVID-19 Clinical management: living guidancecontains the most up-to-date recommendations for the clinical management of people with...

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Clinical management of COVID-19 (14)

24 March 2023

Drugs to prevent COVID-19: living guideline

TheWHO Living guideline: Drugs to prevent COVID-19contains the Organization’s most up-to-date recommendations for the use of drugs to...

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Clinical management of COVID-19 (15)

6 April 2022

Clinical care of severe acute respiratory infections – Tool kit

First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection,...

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COVID-19 Operational tools for health facility and health system planning

15 February 2022

WHO COVID-19 Essential Supplies Forecasting Tool (COVID-ESFT) v4.1

The WHO COVID-19 Essential Supplies Forecasting Tool (ESFT) assists governments, partners, and other stakeholders to forecast the necessary volume of personal...

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Clinical management of COVID-19 (16)

19 November 2020

Priority medical devices list for the COVID-19 response and associated technical specifications

This document describes themedical devices required for the clinical management of COVID-19,selected and prioritized according tothe...

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Clinical management of COVID-19 (17)

26 June 2020

Biomedical equipment for COVID-19 case management - inventory tool: Interim guidance

Access the tool:Biomedical equipment for COVID-19 case management: toolUse and contentCountries can use this tool to collect in-depth facility inventories...

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Clinical management of COVID-19 (2025)
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